Total Vision Solutions, All in One Place
Expert care from trusted leaders in eye health—delivered by the region’s most experienced eye doctors.
Optimal Vision Care For Every Age

Tired of wearing glasses or contacts?
Try LASIK! It's a quick, safe and effective corrective eye procedure with over 20 years of proven results.

Trouble reading on your smartphone?
We offer a variety of treatment methods to help you significantly reduce, and even eliminate, the need for reading glasses.

Is driving at night an issue?
It's normal to notice changes in your vision with age. We can help preserve your sight to help you maintain a vibrant, active lifestyle.
Wesson and Mothershed Eye Center: Committed to Excellence in Eye Care
At Wesson and Mothershed Eye Center we proudly offer eye care and eyewear to help the whole family see clearly and look great!
Our local eye clinic is located Northwest of Martin Luther King Drive and I-22, on North Gloster Street. Our team offers a full range of basic eye care services. These include eye exams for adults and kids, as well as updates to glasses and contact lens prescriptions.
We also have the equipment and training to provide specialty services, including treatment for dry eyes, scleral lens fittings, medical optometry, ortho-k for adults, and myopia management.
Our optical team works hard to bring you a great selection of stylish, comfortable, and durable glasses frames. Popular eyewear brands we carry include Vera Wang, Kate Spade, and Lacoste.
Want to know more about how we can help you see clearly and look great? Come visit our Tupelo eye clinic, or give us a call at 662-844-3555, today!
See the Brilliance of Every Day
The ophthalmologists and optometrists at Wesson and Mothershed Eye Center have expertise in applying the most recent, proven, and medical treatments that offer exceptional outcomes in eye care.
We not only test and treat a range of eye conditions but also provide you with routine prescription checks, such as glasses and contact lens prescriptions, and offer a wide array of frames and lenses to choose from.

Our Most Popular Eye Care Services

Have you got eyes that itch all the time? Or do your eyes often feel dry and uncomfortable? Our eyecare professionals will thoroughly evaluate your eyes to detect the cause of your dry eye symptoms and offer you effective treatment to alleviate your discomfort.

Cataract surgery involves removing the cataract (cloudy lens) and replacing it with a new lens to provide patients with better vision. We at Wesson and Mothershed Eye Center provide cataract surgery at our Medicare Approved facility in Tupelo, restoring patients' eye health and quality of life.

Ever wonder how you could find the perfect pair of lenses for all ranges? Whether you need lenses for near vision, distance vision, or progressive lenses for both, our edging lab crafts the finest digital lenses available. You will be amazed by the precision and clarity of our digital lenses, after all, seeing is believing!
What Our Patients Are Saying

Wesson and Mothershed Eye Center
Eye Disease Management & Treatment
Occupational Lenses in Tupelo—Vision Support for Your Work Environment.
Whether you’re working at a screen, presenting to a room, or creating at your workstation, our occupational lenses are precisely optimized for your daily routine. With in-office technology, we measure and build lenses that match your world—not just your prescription.

Optical Frames and Sunglasses



Our Blog
Mississippi's unique climate and work culture call for eyewear that blends durability with style. From fog-resistant lenses to lightweight frames that handle the heat, there’s more to choosing glasses than just your prescription. This guide helps patients in Tupelo and surrounding areas find eyewear that fits their needs—and their face.
Pediatric eye exams are an essential part of back-to-school prep. Regular exams catch vision issues early, support learning, and keep children’s eyes healthy. From myopia management to light sensitivity relief, Wesson and Mothershed Eye Center offers advanced solutions tailored for growing eyes.
Dry eye syndrome is increasingly common in the South due to weather conditions, screen time, and age-related changes. Common symptoms include burning, grittiness, and blurred vision, often caused by tear imbalance or poor-quality tears. Fortunately, Tupelo residents have access to effective treatments—from advanced in-office therapies to personalized care at Wesson and Mothershed Eye Center.